Topic description
Specific Challenge:
Complex multi-component, hybrid, functional nanomaterials and High Aspect Ratio Nanoparticles (NMs&HARNs), present both innovation potential and challenges in terms of assessing the risk in different environments. Concerns for these multi-component nanomaterials result from differing rates of degradation and toxicities of the separate and interacting components and their different interactions with biological and environmental systems. Previous projects on Safe by Design have developed risk assessment tools and strategies, however they were only implemented within the context of an example case study. The implementation of these tools and approach at scale is still remains to be achieved. The challenge is to develop and implement Safe by Design concepts for products incorporating such nanomaterials and to understand their impact on manufacturing processes, on product performance, and on the environment and on health.
Scope:
The proposals should:
- Coordinate with the projects from NMBP-15-2019, and focus on filling the gaps in the current understanding of exposure and hazard characteristics of NMs&HARNs especially those arising from their unique properties, as well as assessing the extent of and rates by which variations of environment modify the nanoparticle properties and agglomeration rates;
- Use multiscale modelling approaches to identify how different patterns of release may influence physiological responses and how elements of multi-component nanomaterials interact with each other, with other NMs, and other chemicals leading ultimately to mixture toxicity;
Develop knowledge and tools for Safe by Design approaches that support the development of multi-component nano-enabled products with reduced persistence, exposure and hazard. This should be coupled with developing multi-scale modelling approaches to evaluate the effectiveness of the proposed safe-by-design strategies
Relevant indicators and metrics, with baseline values, must be clearly stated in the proposal and should be in line with previous efforts on Safe by Design. For this topic a parallel call scheme is envisaged with the USA-NNI. Resulting projects should establish close cooperation mechanisms. Therefore, proposals should foresee a dedicated work package for cooperation and earmark appropriate resources.
Activities should start at TRL 4 and achieve TRL 6 at the end of the project.
The Commission considers that proposals requesting a contribution from the EU between EUR 6 and 8 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.
Expected Impact:
- Implementation of validated safe-by-design strategies including enabling their uptake and utilization by SMEs;
- Recommendations on adaptation and improvement of current guidelines for exposure and hazard assessment of multi-component NMs as necessary;
- A categorisation scheme to cluster sector-specific multi-component nanomaterials by assessing nano-specific properties in real-life environments;
- Integration of specific characteristics of multi-component NMs, including the potential for mixture effects, in risk assessment and safe-by-design strategies.
Cross-cutting Priorities:
International cooperation
Open Innovation
Open Science
Keywords
Surface science and nanostructures
Competitiveness, innovation, research and developm
Entrepreneurship
Design-Manufacturing
Cement, Ceramics and composites
Environmental planning
Environmental chemistry
Carbon-based polymers and activated carbons
Public and environmental health
Production technology, process engineering
Nanotechnology, nano-materials, nano engineering
Occupational safety
Graphene, layered material
Risks and vulnerabilities assessment
Paint and coatings
Chemical engineering, technical chemistry
Innovation strategies
Industrial chemistry
Knowledge transfer
Catalysis
Nano-materials (production and properties)
Regulatory framework for innovation
Product innovation
Graphene, 2D materials
Surface modification
Piloting
Risk reduction
Polymers and plastics
Semiconductors and Nanotechnology
New materials: oxides, alloys, composite, organic-
Materials engineering (biomaterials, metals, ceram
Environment and health risks, occupational medicin
Risks assessment, modelling and impact reduction
Toxicology
Quality management
Tags
NMBP-16-2020
H2020-NMBP-TO-IND-2020
Design innovation